Bioactive Glass

Mo-Sci Health Care has extensive experience in the manufacture of bioactive glasses. Bioactive glasses have the ability to bond to soft and/or hard tissue and are biodegradable in the body. Our staff of glass engineers and technicians can research, develop and produce glass which is custom-made to fit your particular application.

Manufacturing Facilities

Great care is taken in the manufacturing (batching, melting, grinding, forming, and packaging) of these specialized glasses to assure that they meet the high standards for medical products. These glasses are made from high purity (analytical and reagent grade) chemicals, keeping unwanted trace impurities to a minimum. Precious metal or high purity ceramic crucibles are used to melt glasses in dedicated furnaces and processed in an environmentally controlled space.

Composition and Properties

Standard compositions of bioactive glasses are shown below in the table. Custom compositions are available upon request. New glasses are being commercialized all the time, so please check back or contact Mo-Sci if you need something beyond our standard offerings.

Target Compositions (wt%)

Glass GL # SiO2 CaO Na2O P2O5 B2O3 K2O MgO CuO SrO ZnO Fe2O3
45S5 0160ŧ 45.0 24.5 24.5 6.0 - - - - - - -
S53P4 0804ŧ 53.0 20.0 23.0 4.0 - - - - - - -
13-93 0811*ŧ 53.0 20.0 6.0 4.0 - 12.0 5.0 - - - -
NA 1550*ŧ - 20.0 6.0 4.0 53.0 12.0 5.0 - - - -
NA 1605*ŧ - 20.0 6.0 4.0 51.6 12.0 5.0 0.4 - 1.0 -
NA 1624*ŧ - 20.0 6.0 4.0 49.2 12.0 5.0 0.4 2.0 1.0 0.4
NA 1708ŧ - 16.8 12.4 70.8 - - - - - - -

Note: Some glass compositions (*) or form factors (ŧ) will require licensing as they are protected by U.S. and International Patents. If you are looking for a new technology to differentiate from the rest of your industry, please contact Mo-Sci for more details.

Applications

Bioactive glasses are available in a wide variety of different forms, ranging from cast shapes, quenched frit, rods, fibers, disks, spheres, porous scaffolds, and millimeter to submicron sized powders. These can be surface-treated or modified as needed for particular applications. Depending on the composition, thin plates similar to microscope slides may be available as a custom item through R&D.

Uses include: Blood vessel

  • Implant components for bone grafting biomaterials such as granules, putty, strips, or porous scaffolds
  • Repair of periodontal defects
  • Cranial and maxillofacial repair
  • Dental applications such as a desensitization component for toothpaste
  • Bioactive coatings for metal, ceramics, or plastics
  • Fiber reinforcement for composites
  • Wound care for traumatic or nonhealing wounds
  • Hemostatic devices for blood loss control
  • Stimulation of vascular regeneration
  • Nerve repair