Osteofelt is a dynamic bone grafting scaffold composed of a mixture of bioactive glass fibers in the micron and submicron size range and beads that upon implantation stimulates bone growth and repair. The dynamic nature of this graft allows for optimal handling during implantation. The material has the consistency of a cotton ball when dry, but the graft contains an array of pore sizes ranging from nanometers to millimeters which is advantageous for drug or growth factor delivery applications or for absorbing bone marrow aspirate. Osteofelt is available in a variety of traditional bioactive glass compositions or a bioactive glass can be specially developed to suit your specific needs.
The image of the left is a magnified view of Osteofelt which contains microspheres (vertical arrows) intermixed with micron and submicron sized bioactive glass fibers. The image on the right shows a highly magnified image of the bioactive glass fibers. Typically, there is a fiber size distribution that varies from several hundred nanometers to tens of micrometers depending on the Osteofelt composition.
Osteofelt is composed of bioactive glass, which means the fibers react with the body fluids and the glass converts to a bone-like material that is later remodeled by bone cells. An example of what the Osteofelt fibers look like during conversion is shown above where the fiber was reacted in a simulated body fluid, and has formed a highly porous surface that is similar to the inorganic component of natural bone.